THERAPEUTIC GROUP: Nasal decongestants and other preparations for topical use
Indications Silver Protein
Proteinated Silver is used as an ear antiseptic, topical antiseptic and nasal decongestant
Mechanism of action Silver protein
Protein silver, often called vitellin silver, is an active ingredient consisting of organic molecules and silver ions used successfully in the clinical setting both as an antiseptic and as a decongestant of the nasal mucosa.
The mostly bacteriostatic effect is determined by the ability of this molecule to inhibit bacterial replication by exerting a visible pro-oxidant effect, such as to alter the normal metabolic capacity of the microorganism, firstly inducing the blocking of replication processes and subsequently its death.
The decongestant effect, on the other hand, has not yet been fully clarified, although the ability to determine a precipitation of the serum exudate proteins is hypothesized, resulting in a better compartmentalization of the water state and a reduction in associated edema.
All this is facilitated by the good pharmacokinetic properties of the silver proteinate, which limit the systemic absorption of the ion and the potential side effects.
Studies carried out and clinical efficacy
All the studies relating to the efficacy of colloidal silver in the clinical setting are particularly dated, demonstrating the common use of this active ingredient in clinical practice.
Despite this, recent scientific evidence, some of which published below, demonstrates the new potential uses of Silver in medicine, dispelling some myths and opening instead therapeutic perspectives of particular clinical interest.
SILVER IN THE HEALING OF WOUNDS
Med Hypotheses. 2012 Oct;79(4):542-3. doi: 10.1016/j.mehy.2012.07.015. Epub 2012 Aug 3.
Argentum-quarz solution in the treatment of anorectal fistulas: is it possible a conservative approach?
Tomasello G, Bellavia M, Damiani F, Damiano G, Palumbo VD, Fiorentini T, Puleio R, Spinelli G, Damiani P, Ficarella S, Bruno A, Lo Monte AI.
Study that tests the potential of Silver in wound healing, and in particular of anoretal fistulas, thus potentially saving surgical therapy, which is decidedly more invasive and with greater complications.
SILVER IN HOMEOPATHY
Complement Ther Med. 2003 Jun;11(2):65-71.
The effects of homeopathic Argentum nitricum on test anxiety.
Baker DG, Myers SP, Howden I, Brooks L.
Study highlighting the futility of homeopathic silver in the treatment of generalized anxiety disorder in the university student population.
Method of use and dosage
Protein Silver is found in ear drops or nasal instillation drops concentrated at 0,5% - 1% and 2%.
According to medical indication, it is generally recommended to instill 1 or 2 drops directly into the ear canal several times a day, and 1-3 drops per nostril several times a day.
Warnings Silver Protein
Prolonged use of Silver Protein could lead to the onset of hypersensitivity reactions to the active ingredient such as to require the suspension of the therapy in progress.
It is also advisable to keep the drug out of the reach of children, to avoid its inappropriate use and potentially very dangerous ingestion.
PREGNANCY AND BREASTFEEDING
The use of silver protein in pregnancy and lactation should be limited to cases of real need and obviously supervised by your gynecologist.
No drug interactions worthy of clinical note are currently known.
Contraindications Silver Protein
The use of Silver Protein is contraindicated in patients hypersensitive to the active ingredient or to structurally related drugs.
Undesirable Effects - Side Effects
The use of silver protein, especially if prolonged over time, could determine the onset of local adverse reactions such as burning, redness and pain.
Proteinated Silver is a non-prescription drug.
The information on Silver Protein published on this page may be out of date or incomplete. For a correct use of this information, see the Disclaimer and useful information page.